ICSI – Intra Cytoplasmic Sperm Injection

Intracytoplasmic sperm injection (ICSI) is a technique in which a single sperm is injected into a single mature oocyte under favourable temperature and culture conditions

Has been a milestone in treating male infertility.

Male casuses

  • low sperm numbers
  • low sperm motility
  • poor sperm morphology
  • globozoospermia
  • high antibody titres
  • retrograde ejaculation
  • surgically retrieved sperm

Female causes

  • advanced maternal age
  • low ovarian reserve/poor responder
  • thick zonae
  • high rate of polyspermia
  • unexpected previous fertilisation failure (occult male factor?)
  • PGD

Intracytoplasmic sperm injection (ICSI) is a technique in which a single sperm is injected into a single mature oocyte under favourable temperature and culture conditions.