You are currently viewing Signs and Symptoms of High Estrogen in Females – Causes & Treatment

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Estrogen is a hormone primarily produced by the ovaries, and to a lesser extent, by the adrenal glands and fat cells. Its role is vital in developing and maintaining the female reproductive system, including the growth and maturation of breasts, uterus, and vagina.

During the menstrual cycle, estrogen thickens the uterine lining, preparing it for a fertilized egg’s potential implantation. Additionally, it regulates the menstrual cycle by controlling the production of LH and FSH from the pituitary gland.

However, having too little or too much estrogen in women can adversely affect women’s health. Low estrogen levels can cause vaginal dryness and decreased bone density. Conversely, too much estrogen levels can increase the risk of breast and ovarian cancer. Abnormally low or increased estrogen levels can cause menstrual irregularities.

Hence, it is crucial for women to maintain a healthy balance of estrogen throughout their lives to support reproductive health, bone health, and overall well-being.

What Does High Estrogen in Women Mean?

When estrogen levels in women go beyond the normal physiological range, it’s known as hyperestrogenism or high estrogen levels. Excess levels of estrogen have been associated with an increased risk of breast cancer, uterine cancer, and other cancers. Additionally, women with hyperestrogenism have a higher risk of developing blood clots, stroke, and heart disease.

What are the Causes of Excess Estrogen Levels in Females?

Increased levels of estrogen in women can be caused by various factors, including:

Hormonal imbalances:

Hormonal imbalances in the body can lead to an excess of estrogen.


Fat cells produce estrone (a form of estrogen), and excess body fat can lead to excess estrogen in women.

low self-esteem woman with obesity


Certain medications such as hormone replacement therapy, can lead to increased level of estrogen levels.


During pregnancy, estrogen levels increase to support fetal development, and after delivery, they may remain elevated for a period of time.

Ovarian tumors:

Ovarian tumors, particularly those that produce estrogen, can lead to excess estrogen in women.

Thyroid disorders:

An overactive thyroid gland can cause high estrogen levels due to the increased conversion of androgens to estrogen.

Liver disease:

Liver disease can impair the liver’s ability to metabolize and eliminate excess estrogen, leading to excess levels in the body.

Certain foods:

Some foods, such as soy products, can contain phytoestrogens that mimic estrogen in the body and lead to elevated estrogen in women.

Environmental factors:

Exposure to certain environmental toxins, such as pesticides and plastics, can disrupt the body’s hormonal balance and lead to increased level of estrogen levels.

What are the various Elevated Estrogen Symptoms in Females?

High estrogen symptoms in women

The high estrogen symptoms in females include the following:

  • Irregular menstrual periods or heavy bleeding
  • Breast tenderness or swelling
  • Bloating or water retention
  • Mood swings, irritability, or depression
  • Headaches or migraines
  • Fatigue or lethargy
  • Weight gain or difficulty losing weight
  • Changes in skin or hair texture
  • Difficulty sleeping or insomnia

It’s important to note that some of these elevated estrogen symptoms may also be caused by other conditions, so it’s important to see a healthcare provider for an accurate diagnosis.

What are Normal Estrogen Levels in Women?

Normal estrogen levels in women can vary depending on age, menstrual cycle, and other health factors. In premenopausal women, estrogen levels are typically measured during the follicular phase of the menstrual cycle, i.e. the first 14 days in a cycle of 28 days.

  • The normal range for estradiol (the most potent form of estrogen) during this phase is typically between 30 and 400 pg/mL (picograms per milliliter).
  • During the luteal phase (days 15-28), estradiol levels typically decrease, with a normal range of 15 to 275 pg/mL.
  • In postmenopausal women, normal estrogen levels are lower, with a range of less than 10 to 30 pg/mL.

Keep in mind that reference ranges for estrogen levels can differ depending on the laboratory and assay used. However, it’s worth noting that estrogen levels don’t necessarily provide a comprehensive understanding of a woman’s reproductive health. Other hormones like progesterone and FSH also have significant roles in the menstrual cycle.

To get a more accurate evaluation of estrogen levels, it’s essential to consider a woman’s overall health and reproductive status and seek personalized guidance and treatment from a healthcare provider.

How to Flush Out Excess Estrogen Levels in Women?

To flush out excess estrogen, there are a few strategies that can be employed:

1. Increase fiber intake:

It can help improve bowel movements and promote the elimination of excess estrogen through faecal matter.

2. Consume cruciferous vegetables:

Vegetables like broccoli, kale, and cauliflower contain compounds that support the liver in breaking down estrogen and excreting it from the body.

3. Reduce alcohol intake:

Excessive alcohol consumption can interfere with the liver’s ability to metabolize and eliminate excess estrogen.

4. Exercise regularly:

It improves blood circulation and supports the lymphatic system in removing excess estrogen from the body.

5. Consider supplements:

Certain supplements, such as calcium-d-glucarate and DIM (diindolylmethane), can aid in the detoxification and removal of excess estrogen from the body.

young pregnant woman taking supplements

It’s important to note that while these strategies may be helpful in reducing excess estrogen levels, it’s always best to consult with a healthcare professional for personalized guidance and to address any underlying health issues.

Treatment for High Estrogen in Females

Under medical supervision, you can undergo any of the following treatments for increased level of estrogen in females :

Hormonal therapy:

This involves the use of medications that reduce the amount of estrogen in the body. Examples include anti-estrogen drugs like Tamoxifen or aromatase inhibitors like Letrozole or Anastrozole.

Surgical intervention:

In severe cases, a surgical procedure known as oophorectomy may be recommended. This involves removing the ovaries, which are the main source of estrogen in females.

Lifestyle modifications:

Lifestyle changes such as a healthy diet, regular exercise, and stress reduction techniques can help to lower estrogen levels naturally.

In conclusion, understanding the signs and symptoms of high estrogen levels in females is crucial for early detection and intervention. By recognizing the manifestations such as irregular menstrual cycles, mood changes, and weight gain, individuals can seek appropriate medical guidance to address potential hormonal imbalances. With customized treatment approaches, including lifestyle modifications and medication, individuals can effectively manage high estrogen levels and promote overall hormonal health and well-being.


Yes, high estrogen levels in women’s bodies can cause fertility issues by disrupting the delicate balance of hormones required for ovulation.

If estrogen levels are high in females, it can lead to symptoms such as irregular periods, mood swings, breast tenderness, and weight gain.

It is not necessarily better to have high or low estrogen levels, as both extremes can lead to health issues. It is important to maintain a balance of hormones for optimal health.

Assessment of estrogen levels through symptoms such as irregular menstrual cycles, mood swings, and changes in libido can help determine if estrogen levels are high or low, with confirmation through hormone testing.

Factors that can increase estrogen levels in females include obesity, hormonal medications like birth control pills, hormone replacement therapy, certain foods rich in phytoestrogens, and environmental exposures to endocrine-disrupting chemicals.

Foods to avoid with high estrogen include soy products, flaxseeds, processed foods, and alcohol, which can potentially exacerbate hormonal imbalance.

Dr. Shefali Jain

Dr. Shefali Jain is Gynecologist, Obstetrician & Infertility Specialist in Indore with more than 27 years of experience in the field of ART with highest success rate. She has received many awards for her exceptional work in the field of infertility. She has been an invited speaker to many national and international conferences.